Remote ischemic preconditioning as treatment for non-ischemic gastrointestinal disorders: Beyond ischemia-reperfusion injury
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چکیده
منابع مشابه
The Effects of Remote Ischemic Preconditioning and N-Acetylcysteine with Remote Ischemic Preconditioning in Rat Hepatic Ischemia Reperfusion Injury Model
BACKGROUND Remote ischemic preconditioning (RIP) and pharmacological preconditioning are the effective methods that can be used to prevent ischemia reperfusion (IR) injury. The aim of this study was to evaluate the effects of RIP and N-Acetylcysteine (NAC) with RIP in the rat hepatic IR injury model. MATERIALS AND METHODS 28 rats were divided into 4 groups. Group I (sham): only laparotomy was...
متن کاملPreconditioning Strategies for Kidney Ischemia Reperfusion Injury: Implications of the “Time-Window” in Remote Ischemic Preconditioning
Remote ischemic preconditioning (IP) is a potential renoprotective strategy. However, there has been no demonstrated result in large animals and the role of time window in remote IP remains to be defined. Using a single-kidney porcine model, we evaluated organ protective function of remote IP in renal ischemia reperfusion injury. Fifteen Yorkshire pigs, 20 weeks old and weighing 35-38 kg were u...
متن کاملIschemic preconditioning in hepatic ischemic-reperfusion injury
http://dx.doi.org/10.1016/j.fjs.2016. 1682-606X/Copyright a 2016, Taiwan S NC-ND license (http://creativecommo Abstract Background/Introduction: Ischemic preconditioning is a method in which brief periods of ischemia render tissues resistant to injury resulting from prolonged ischemia and reperfusion, so-called ischemiaereperfusion injury. Purpose: To elucidate the possible protective role of i...
متن کاملIschemic Preconditioning Promotes Autophagy and Alleviates Renal Ischemia/Reperfusion Injury
Autophagy is important for cellular survival during renal ischemia/reperfusion (I/R) injury. Ischemic preconditioning (IPC) has a strong renoprotective effect during renal I/R. Our study here aimed to explore the effect of IPC on autophagy during renal I/R injury. Rats were subjected to unilateral renal ischemia with or without prior IPC. Hypoxia/reoxygenation (H/R) injury was induced in HK-2 c...
متن کاملRole of ischemic preconditioning in hepatic ischemia-reperfusion injury.
BACKGROUND Investigation into less traumatic method of vascular occlusion during liver resection is the actual problem in hepatic surgery because of high level of complications such as liver failure. In this connection, the goal of our study was to determine the optimal model of vascular clamping. The research showed that vascular occlusion with ischemic preconditioning in the mode 5/10/15 the ...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2014
ISSN: 1007-9327
DOI: 10.3748/wjg.v20.i13.3572